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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSMC3IPPSMC3 interacting protein. (234 aa)    
Predicted Functional Partners:
SPO11
SPO11 initiator of meiotic double stranded breaks.
    
 
 0.734
MSH4
MutS homolog 4.
   
  
 0.734
RAD51B
RAD51 paralog B.
   
 0.688
RAD51
RAD51 recombinase; Belongs to the RecA family.
   
 0.672
HFM1
Helicase for meiosis 1.
      
 0.612
RAD51C
RAD51 paralog C.
   
 0.594
KNL1
Kinetochore scaffold 1.
   
 0.589
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 
  0.585
MCM8
MCM domain-containing protein; Belongs to the MCM family.
      
 0.541
FANCL
FA complementation group L.
   
  
 0.517
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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