Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSC1TSC complex subunit 1. (1164 aa)    
Predicted Functional Partners:
TSC2
TSC complex subunit 2.
   
 0.999
TBC1D7
TBC1 domain family member 7.
    
 0.997
RHEB
Uncharacterized protein.
    
 0.995
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.985
AKT2
AKT serine/threonine kinase 2.
    
 0.982
PRKAA2
Non-specific serine/threonine protein kinase.
    
 0.980
AKT3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.978
PRKAB2
Protein kinase AMP-activated non-catalytic subunit beta 2.
   
 0.964
TTC33
Non-specific serine/threonine protein kinase.
    
 0.964
PRKAB1
Protein kinase AMP-activated non-catalytic subunit beta 1.
   
 0.963
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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