Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NLRP8NLR family pyrin domain containing 8. (1031 aa)    
Predicted Functional Partners:
MEFV
MEFV innate immuity regulator, pyrin.
  
   
 0.725
C19orf85
Chromosome 19 open reading frame 85.
      
 0.593
TMEM238
Transmembrane protein 238.
      
 0.592
CCDC106
Coiled-coil domain-containing protein 106.
      
 0.590
FIZ1
Flt3-interacting zinc finger protein 1.
      
 0.582
ZNF524
Zinc finger protein 524.
      
 0.582
ZNF579
Zinc finger protein 579.
      
 0.582
ZNF444
Zinc finger protein 444.
      
 0.582
RFPL4A
Uncharacterized protein.
      
 0.582
TMEM150B
Transmembrane protein 150B.
      
 0.582
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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