Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CTSHCathepsin H; Belongs to the peptidase C1 family. (335 aa)    
Predicted Functional Partners:
BID
BH3 interacting domain death agonist.
   
 
 0.904
BCL2L1
Bcl-2-like protein 1 isoform 1.
     
 0.902
BCL2
BCL2 apoptosis regulator.
     
 0.901
SFTPB
Surfactant protein B.
   
 
 0.811
CRISP1
Cysteine-rich secretory protein 1; May have a role in sperm-egg fusion and maturation.
   
 
 0.805
CTSL
Cathepsin L; Belongs to the peptidase C1 family.
   
 0.765
LOC719235
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
 0.742
SFTPC
Pulmonary surfactant-associated protein C; Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
   
 
 0.742
NAPSA
Napsin A aspartic peptidase; Belongs to the peptidase A1 family.
   
 0.742
CLN5
Uncharacterized protein.
   
  
 0.741
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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