node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CREBBP | EGR1 | ENSMMUP00000065708 | ENSMMUP00000077690 | CREB-binding protein isoform a. | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | 0.648 |
CREBBP | EGR2 | ENSMMUP00000065708 | ENSMMUP00000081151 | CREB-binding protein isoform a. | Uncharacterized protein. | 0.927 |
CREBBP | EGR3 | ENSMMUP00000065708 | ENSMMUP00000075082 | CREB-binding protein isoform a. | Early growth response 3. | 0.939 |
CREBBP | EP300 | ENSMMUP00000065708 | ENSMMUP00000076664 | CREB-binding protein isoform a. | Histone acetyltransferase p300. | 0.998 |
CREBBP | FOS | ENSMMUP00000065708 | ENSMMUP00000071593 | CREB-binding protein isoform a. | V-fos FBJ murine osteosarcoma viral oncogene-like protein. | 0.804 |
CREBBP | FOSB | ENSMMUP00000065708 | ENSMMUP00000060353 | CREB-binding protein isoform a. | BZIP domain-containing protein. | 0.480 |
EGR1 | CREBBP | ENSMMUP00000077690 | ENSMMUP00000065708 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | CREB-binding protein isoform a. | 0.648 |
EGR1 | EGR2 | ENSMMUP00000077690 | ENSMMUP00000081151 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | Uncharacterized protein. | 0.871 |
EGR1 | EGR3 | ENSMMUP00000077690 | ENSMMUP00000075082 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | Early growth response 3. | 0.703 |
EGR1 | EP300 | ENSMMUP00000077690 | ENSMMUP00000076664 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | Histone acetyltransferase p300. | 0.667 |
EGR1 | FOS | ENSMMUP00000077690 | ENSMMUP00000071593 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | V-fos FBJ murine osteosarcoma viral oncogene-like protein. | 0.967 |
EGR1 | FOSB | ENSMMUP00000077690 | ENSMMUP00000060353 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | BZIP domain-containing protein. | 0.916 |
EGR1 | NAB1 | ENSMMUP00000077690 | ENSMMUP00000080675 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | Uncharacterized protein. | 0.814 |
EGR1 | NAB2 | ENSMMUP00000077690 | ENSMMUP00000068570 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | NGFI-A-binding protein 2. | 0.840 |
EGR2 | CREBBP | ENSMMUP00000081151 | ENSMMUP00000065708 | Uncharacterized protein. | CREB-binding protein isoform a. | 0.927 |
EGR2 | EGR1 | ENSMMUP00000081151 | ENSMMUP00000077690 | Uncharacterized protein. | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. | 0.871 |
EGR2 | EGR3 | ENSMMUP00000081151 | ENSMMUP00000075082 | Uncharacterized protein. | Early growth response 3. | 0.980 |
EGR2 | EP300 | ENSMMUP00000081151 | ENSMMUP00000076664 | Uncharacterized protein. | Histone acetyltransferase p300. | 0.920 |
EGR2 | FOS | ENSMMUP00000081151 | ENSMMUP00000071593 | Uncharacterized protein. | V-fos FBJ murine osteosarcoma viral oncogene-like protein. | 0.807 |
EGR2 | FOSB | ENSMMUP00000081151 | ENSMMUP00000060353 | Uncharacterized protein. | BZIP domain-containing protein. | 0.831 |