Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM111AFamily with sequence similarity 111 member A. (611 aa)    
Predicted Functional Partners:
FBXW7
F-box/WD repeat-containing protein 7 isoform 1.
   
  
 0.750
KLHL38
Kelch like family member 38.
      
 0.727
SPRTN
SprT-like N-terminal domain.
   
 
 0.715
VPS39
Uncharacterized protein.
      
 0.713
ARHGAP31
Rho GTPase activating protein 31.
      
 0.632
ASXL1
ASXL transcriptional regulator 1.
     
 0.619
CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial; Belongs to the carnitine/choline acetyltransferase family.
   
  
 0.619
PGBD4
PiggyBac transposable element derived 4.
      
 0.602
DFFB
DNA fragmentation factor subunit beta.
    
   0.598
TCTN1
Tectonic family member 1.
      
 0.589
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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