NRG2 protein (Macaca mulatta) - STRING interaction network

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[Homology]

Score

NRG2

Neuregulin 2. (851 aa)

Predicted Functional Partners:

ERBB4

0.998

ERBB3

0.998

ERBB2

0.993

EGFR

0.991

NRG4

0.988

NRG1

0.977

NRG3

0.928

EREG

0.687

EGF

0.667

BTC

0.617

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTC	EGF	ENSMMUP00000076344	ENSMMUP00000013132	Betacellulin.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.806
BTC	EGFR	ENSMMUP00000076344	ENSMMUP00000046120	Betacellulin.	Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least [...]	0.990
BTC	ERBB2	ENSMMUP00000076344	ENSMMUP00000064366	Betacellulin.	Receptor protein-tyrosine kinase.	0.825
BTC	ERBB3	ENSMMUP00000076344	ENSMMUP00000050150	Betacellulin.	Receptor tyrosine-protein kinase erbB-3 isoform 1.	0.830
BTC	ERBB4	ENSMMUP00000076344	ENSMMUP00000002247	Betacellulin.	Receptor protein-tyrosine kinase.	0.991
BTC	EREG	ENSMMUP00000076344	ENSMMUP00000080811	Betacellulin.	Proepiregulin.	0.809
BTC	NRG1	ENSMMUP00000076344	ENSMMUP00000064397	Betacellulin.	Neuregulin 1.	0.692
BTC	NRG2	ENSMMUP00000076344	ENSMMUP00000013491	Betacellulin.	Neuregulin 2.	0.617
BTC	NRG3	ENSMMUP00000076344	ENSMMUP00000022878	Betacellulin.	Neuregulin 3.	0.400
BTC	NRG4	ENSMMUP00000076344	ENSMMUP00000033410	Betacellulin.	Neuregulin 4.	0.676
EGF	BTC	ENSMMUP00000013132	ENSMMUP00000076344	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Betacellulin.	0.806
EGF	EGFR	ENSMMUP00000013132	ENSMMUP00000046120	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least [...]	0.999
EGF	ERBB2	ENSMMUP00000013132	ENSMMUP00000064366	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.997
EGF	ERBB3	ENSMMUP00000013132	ENSMMUP00000050150	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor tyrosine-protein kinase erbB-3 isoform 1.	0.993
EGF	ERBB4	ENSMMUP00000013132	ENSMMUP00000002247	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.975
EGF	EREG	ENSMMUP00000013132	ENSMMUP00000080811	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Proepiregulin.	0.754
EGF	NRG1	ENSMMUP00000013132	ENSMMUP00000064397	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Neuregulin 1.	0.833
EGF	NRG2	ENSMMUP00000013132	ENSMMUP00000013491	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Neuregulin 2.	0.667
EGF	NRG3	ENSMMUP00000013132	ENSMMUP00000022878	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Neuregulin 3.	0.466
EGF	NRG4	ENSMMUP00000013132	ENSMMUP00000033410	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Neuregulin 4.	0.556