| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBL | CBLB | ENSMMUP00000059041 | ENSMMUP00000071708 | E3 ubiquitin-protein ligase CBL. | Cbl proto-oncogene B. | 0.975 |
| CBL | GRB2 | ENSMMUP00000059041 | ENSMMUP00000045339 | E3 ubiquitin-protein ligase CBL. | Growth factor receptor-bound protein 2 isoform 1. | 0.996 |
| CBL | INSR | ENSMMUP00000059041 | ENSMMUP00000045695 | E3 ubiquitin-protein ligase CBL. | Insulin receptor subunit alpha; Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated proteins serve as docking proteins for other signaling proteins that contain Src-homology-2 domains (SH2 domain) that specifically recognize different phosphotyrosine residues, including the p85 regulatory subunit of PI3K and SHP2. Phosphorylation of IRSs proteins lea [...] | 0.948 |
| CBL | JAK2 | ENSMMUP00000059041 | ENSMMUP00000019119 | E3 ubiquitin-protein ligase CBL. | Tyrosine-protein kinase. | 0.684 |
| CBL | JAK3 | ENSMMUP00000059041 | ENSMMUP00000014406 | E3 ubiquitin-protein ligase CBL. | Janus kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.423 |
| CBL | LOC114669853 | ENSMMUP00000059041 | ENSMMUP00000062520 | E3 ubiquitin-protein ligase CBL. | Tyrosine-protein kinase. | 0.423 |
| CBL | NTRK1 | ENSMMUP00000059041 | ENSMMUP00000016316 | E3 ubiquitin-protein ligase CBL. | Tyrosine-protein kinase receptor. | 0.433 |
| CBL | SH2B2 | ENSMMUP00000059041 | ENSMMUP00000013535 | E3 ubiquitin-protein ligase CBL. | SH2B adaptor protein 2. | 0.983 |
| CBLB | CBL | ENSMMUP00000071708 | ENSMMUP00000059041 | Cbl proto-oncogene B. | E3 ubiquitin-protein ligase CBL. | 0.975 |
| CBLB | GRB2 | ENSMMUP00000071708 | ENSMMUP00000045339 | Cbl proto-oncogene B. | Growth factor receptor-bound protein 2 isoform 1. | 0.983 |
| CBLB | INSR | ENSMMUP00000071708 | ENSMMUP00000045695 | Cbl proto-oncogene B. | Insulin receptor subunit alpha; Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated proteins serve as docking proteins for other signaling proteins that contain Src-homology-2 domains (SH2 domain) that specifically recognize different phosphotyrosine residues, including the p85 regulatory subunit of PI3K and SHP2. Phosphorylation of IRSs proteins lea [...] | 0.924 |
| CBLB | JAK2 | ENSMMUP00000071708 | ENSMMUP00000019119 | Cbl proto-oncogene B. | Tyrosine-protein kinase. | 0.473 |
| CBLB | JAK3 | ENSMMUP00000071708 | ENSMMUP00000014406 | Cbl proto-oncogene B. | Janus kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.423 |
| CBLB | LOC114669853 | ENSMMUP00000071708 | ENSMMUP00000062520 | Cbl proto-oncogene B. | Tyrosine-protein kinase. | 0.423 |
| CBLB | SH2B2 | ENSMMUP00000071708 | ENSMMUP00000013535 | Cbl proto-oncogene B. | SH2B adaptor protein 2. | 0.971 |
| GRB2 | CBL | ENSMMUP00000045339 | ENSMMUP00000059041 | Growth factor receptor-bound protein 2 isoform 1. | E3 ubiquitin-protein ligase CBL. | 0.996 |
| GRB2 | CBLB | ENSMMUP00000045339 | ENSMMUP00000071708 | Growth factor receptor-bound protein 2 isoform 1. | Cbl proto-oncogene B. | 0.983 |
| GRB2 | INSR | ENSMMUP00000045339 | ENSMMUP00000045695 | Growth factor receptor-bound protein 2 isoform 1. | Insulin receptor subunit alpha; Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated proteins serve as docking proteins for other signaling proteins that contain Src-homology-2 domains (SH2 domain) that specifically recognize different phosphotyrosine residues, including the p85 regulatory subunit of PI3K and SHP2. Phosphorylation of IRSs proteins lea [...] | 0.980 |
| GRB2 | JAK2 | ENSMMUP00000045339 | ENSMMUP00000019119 | Growth factor receptor-bound protein 2 isoform 1. | Tyrosine-protein kinase. | 0.888 |
| GRB2 | JAK3 | ENSMMUP00000045339 | ENSMMUP00000014406 | Growth factor receptor-bound protein 2 isoform 1. | Janus kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.767 |
