Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CCNOCyclin O; Belongs to the cyclin family. (644 aa)    
Predicted Functional Partners:
MCIDAS
Multiciliate differentiation and DNA synthesis associated cell cycle protein.
   
  
 0.870
CDC20B
Cell division cycle 20B.
   
 0.819
CDK3
Cyclin dependent kinase 3; Belongs to the protein kinase superfamily.
   
 0.805
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 
 0.796
CDC20
Cell division cycle protein 20 homolog.
   
 0.765
WEE2
Wee1-like protein kinase.
   
 0.759
DEUP1
Deuterosome assembly protein 1.
    
 
 0.751
CDKN1A
Cyclin-dependent kinase inhibitor 1.
    
 0.728
CCDC78
Coiled-coil domain containing 78.
   
 0.719
PLK4
Polo like kinase 4.
   
 0.703
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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