Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADCY10Adenylate cyclase 10. (1609 aa)    
Predicted Functional Partners:
LOC694289
Uncharacterized protein.
    
 0.958
LOC719662
Guanylate cyclase domain-containing protein.
  
  
 
0.907
CNR1
Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP (By similarity). In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. In [...]
    
 0.903
NUDT2
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical].
   
 
  0.901
ENTPD2
Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family.
     
  0.900
NTPCR
Cancer-related nucleoside-triphosphatase.
     
  0.900
GCH1
GTP cyclohydrolase 1.
     
  0.800
GNAI2
Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1.
    
  0.800
MOCS1
Molybdenum cofactor synthesis 1.
     
  0.800
GNAI3
Guanine nucleotide-binding protein G(K) subunit alpha.
    
  0.748
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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