Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DCAF6Uncharacterized protein. (951 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
    
 0.979
CUL4A
Cullin 4A; Belongs to the cullin family.
   
 0.962
CUL4B
Cullin 4B; Belongs to the cullin family.
   
 0.898
WDR18
WD repeat domain 18.
      
 0.868
ZNF653
Zinc finger protein 653.
      
 0.840
DCAF5
DDB1 and CUL4 associated factor 5.
     
0.807
DCAF12
DDB1 and CUL4 associated factor 12.
   
 
 0.781
DDA1
DET1-and DDB1-associated protein 1.
    
 0.774
DCAF4
DDB1-and CUL4-associated factor 4 isoform 1.
     
 0.765
DCAF4L1
DDB1-and CUL4-associated factor 4-like protein 1.
     
 0.765
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (12%) [HD]