Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FOXA2Forkhead box A2. (457 aa)    
Predicted Functional Partners:
GATA4
GATA binding protein 4.
   
 0.956
OTX2
Orthodenticle homeobox 2.
   
 
 0.947
MIXL1
Mix paired-like homeobox.
   
 
 0.927
TBXT
T-box transcription factor T.
    
 0.912
GATA3
GATA binding protein 3.
   
 0.911
SOX17
SRY-box transcription factor 17.
    
 0.910
RPS6KB2
Non-specific serine/threonine protein kinase.
    
 0.905
RPS6KB1
Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
    
 0.905
EOMES
Eomesodermin.
   
 0.893
GATA6
Transcription factor GATA-6.
   
 0.886
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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