Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLIT1Slit guidance ligand 1. (1534 aa)    
Predicted Functional Partners:
ROBO2
Roundabout guidance receptor 2.
   
 0.999
ROBO1
Roundabout guidance receptor 1.
   
 0.998
ROBO4
Roundabout guidance receptor 4.
   
 0.921
ROBO3
Roundabout guidance receptor 3.
    
 0.894
NEO1
Neogenin 1.
   
 0.695
SEMA4F
Ssemaphorin 4F; Belongs to the semaphorin family.
      
 0.677
NTN1
Netrin 1.
   
 
 0.662
EPHA6
EPH receptor A6.
   
 0.658
SRGAP1
SLIT-ROBO Rho GTPase-activating protein 1.
     
 0.624
SEMA6D
Semaphorin-6D isoform 4; Belongs to the semaphorin family.
      
 0.616
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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