close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GIT2GIT ArfGAP 2. (740 aa)    
Predicted Functional Partners:
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.967
CDC42
Cell division control protein 42 homolog isoform 1.
   
 0.967
SRC
Tyrosine-protein kinase.
     
 0.937
PAK3
Uncharacterized protein.
    
 0.912
ITSN2
Intersectin 2.
   
 
 0.904
ARHGEF7
Rho guanine nucleotide exchange factor 7.
   
 0.904
PAK1
Non-specific serine/threonine protein kinase.
   
 0.861
PXN
Paxillin.
   
 
 0.844
GIT1
GIT ArfGAP 1.
  
 
0.764
PBK
PDZ binding kinase.
     
 0.690
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.