Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARL5AADP-ribosylation factor-like protein 5A isoform 1; Belongs to the small GTPase superfamily. Arf family. (179 aa)    
Predicted Functional Partners:
ARL5B
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
   
   0.788
ARFGAP3
ADP ribosylation factor GTPase activating protein 3.
   
 0.754
BBS2
Bardet-Biedl syndrome 2 protein homolog.
   
 0.715
BBS5
Kelch like family member 41.
   
 0.712
BBS7
Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.
   
 0.694
GBF1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
    
 0.663
ABCF2
Uncharacterized protein.
   
 
 0.654
ARFGAP2
ADP ribosylation factor GTPase activating protein 2.
   
 0.654
COPB1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 0.653
BBS9
Bardet-Biedl syndrome 9.
   
 0.644
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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