Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MESP1Mesoderm posterior bHLH transcription factor 1. (272 aa)    
Predicted Functional Partners:
CCDC38
Coiled-coil domain containing 38.
   
    0.994
NKX2-5
NK2 homeobox 5.
    
 0.805
GATA4
GATA binding protein 4.
   
 0.719
TCF3
Transcription factor 3.
   
 0.609
MINAR1
UPF0258 domain-containing protein.
      
 0.606
ISL1
ISL LIM homeobox 1.
    
 0.586
SOX17
SRY-box transcription factor 17.
    
 
 0.530
GATA6
Transcription factor GATA-6.
   
 0.507
GATA5
GATA binding protein 5.
   
 0.477
AKAP13
A-kinase anchoring protein 13.
      
 0.468
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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