Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADD2Beta-adducin isoform a. (726 aa)    
Predicted Functional Partners:
ADD1
Adducin 1.
   
 0.981
DMTN
Dematin actin binding protein.
   
 0.969
TMOD1
Uncharacterized protein.
   
 
 0.905
SPTB
Spectrin beta chain; Belongs to the spectrin family.
   
 
 0.795
TMOD4
Tropomodulin 4.
    
 
 0.779
TMOD2
Uncharacterized protein.
   
 
 0.779
ANKRD29
Ankyrin repeat domain-containing protein 29.
    
 0.763
ROCK1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
 
 0.732
SPTA1
Spectrin alpha, erythrocytic 1.
   
 
 0.730
SPTBN2
Spectrin beta chain; Belongs to the spectrin family.
   
 
 0.729
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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