node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APELA | APLNR | ENSMMUP00000077641 | ENSMMUP00000013928 | Uncharacterized protein. | Apelin receptor; Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. P [...] | 0.962 |
APELA | GNAI1 | ENSMMUP00000077641 | ENSMMUP00000030898 | Uncharacterized protein. | G protein subunit alpha i1. | 0.800 |
APELA | GNB1 | ENSMMUP00000077641 | ENSMMUP00000066781 | Uncharacterized protein. | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. | 0.800 |
APLNR | APELA | ENSMMUP00000013928 | ENSMMUP00000077641 | Apelin receptor; Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. P [...] | Uncharacterized protein. | 0.962 |
APLNR | GNAI1 | ENSMMUP00000013928 | ENSMMUP00000030898 | Apelin receptor; Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. P [...] | G protein subunit alpha i1. | 0.991 |
APLNR | GNAI2 | ENSMMUP00000013928 | ENSMMUP00000026482 | Apelin receptor; Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. P [...] | Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1. | 0.920 |
APLNR | GNAI3 | ENSMMUP00000013928 | ENSMMUP00000007669 | Apelin receptor; Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. P [...] | Guanine nucleotide-binding protein G(K) subunit alpha. | 0.917 |
APLNR | GNAQ | ENSMMUP00000013928 | ENSMMUP00000061851 | Apelin receptor; Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. P [...] | Guanine nucleotide-binding protein G(Q) subunit alpha. | 0.921 |
APLNR | GNB1 | ENSMMUP00000013928 | ENSMMUP00000066781 | Apelin receptor; Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. P [...] | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. | 0.991 |
APLNR | GNB3 | ENSMMUP00000013928 | ENSMMUP00000006868 | Apelin receptor; Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. P [...] | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. | 0.916 |
APLNR | GNG11 | ENSMMUP00000013928 | ENSMMUP00000051134 | Apelin receptor; Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. P [...] | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.916 |
APLNR | GNG7 | ENSMMUP00000013928 | ENSMMUP00000068383 | Apelin receptor; Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. P [...] | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.917 |
APLNR | GNGT1 | ENSMMUP00000013928 | ENSMMUP00000048892 | Apelin receptor; Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. P [...] | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.918 |
GNAI1 | APELA | ENSMMUP00000030898 | ENSMMUP00000077641 | G protein subunit alpha i1. | Uncharacterized protein. | 0.800 |
GNAI1 | APLNR | ENSMMUP00000030898 | ENSMMUP00000013928 | G protein subunit alpha i1. | Apelin receptor; Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. P [...] | 0.991 |
GNAI1 | GNAI2 | ENSMMUP00000030898 | ENSMMUP00000026482 | G protein subunit alpha i1. | Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1. | 0.968 |
GNAI1 | GNAI3 | ENSMMUP00000030898 | ENSMMUP00000007669 | G protein subunit alpha i1. | Guanine nucleotide-binding protein G(K) subunit alpha. | 0.900 |
GNAI1 | GNB1 | ENSMMUP00000030898 | ENSMMUP00000066781 | G protein subunit alpha i1. | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. | 0.992 |
GNAI1 | GNB3 | ENSMMUP00000030898 | ENSMMUP00000006868 | G protein subunit alpha i1. | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. | 0.885 |
GNAI1 | GNG11 | ENSMMUP00000030898 | ENSMMUP00000051134 | G protein subunit alpha i1. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.860 |