STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTSSCathepsin S; Belongs to the peptidase C1 family. (354 aa)    
Predicted Functional Partners:
CTSD
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
 0.858
TMPRSS2
Transmembrane serine protease 2; Belongs to the peptidase S1 family.
 
   
 0.850
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
  
 
 0.847
NPC1
NPC intracellular cholesterol transporter 1.
   
  
 0.787
ACE2
Angiotensin-converting enzyme.
      
 0.780
MPO
Myeloperoxidase.
   
  
 0.773
CD74
HLA class II histocompatibility antigen gamma chain isoform a.
   
 0.735
LGMN
Legumain preproprotein.
   
 
 0.735
ELANE
Elastase, neutrophil expressed; Belongs to the peptidase S1 family.
     
 0.733
CTSE
Cathepsin E; Belongs to the peptidase A1 family.
   
 0.722
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.