RFXANK protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

RFXANK

Regulatory factor X associated ankyrin containing protein. (314 aa)

Predicted Functional Partners:

RFX5

0.999

RFXAP

0.998

CIITA

0.991

RFX1

0.819

RFX7

0.789

SS18L1

0.741

NLRC5

0.737

HDAC4

0.727

RFX6

0.679

RFX2

0.668

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CIITA	RFX1	ENSMMUP00000073242	ENSMMUP00000024954	Class II major histocompatibility complex transactivator.	Regulatory factor X1.	0.654
CIITA	RFX5	ENSMMUP00000073242	ENSMMUP00000072291	Class II major histocompatibility complex transactivator.	DNA-binding protein RFX5.	0.993
CIITA	RFXANK	ENSMMUP00000073242	ENSMMUP00000014049	Class II major histocompatibility complex transactivator.	Regulatory factor X associated ankyrin containing protein.	0.991
CIITA	RFXAP	ENSMMUP00000073242	ENSMMUP00000012971	Class II major histocompatibility complex transactivator.	Regulatory factor X-associated protein.	0.970
HDAC4	RFXANK	ENSMMUP00000007984	ENSMMUP00000014049	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Regulatory factor X associated ankyrin containing protein.	0.727
NLRC5	RFX5	ENSMMUP00000078798	ENSMMUP00000072291	NLR family CARD domain containing 5.	DNA-binding protein RFX5.	0.532
NLRC5	RFXANK	ENSMMUP00000078798	ENSMMUP00000014049	NLR family CARD domain containing 5.	Regulatory factor X associated ankyrin containing protein.	0.737
NLRC5	RFXAP	ENSMMUP00000078798	ENSMMUP00000012971	NLR family CARD domain containing 5.	Regulatory factor X-associated protein.	0.744
RFX1	CIITA	ENSMMUP00000024954	ENSMMUP00000073242	Regulatory factor X1.	Class II major histocompatibility complex transactivator.	0.654
RFX1	RFXANK	ENSMMUP00000024954	ENSMMUP00000014049	Regulatory factor X1.	Regulatory factor X associated ankyrin containing protein.	0.819
RFX1	RFXAP	ENSMMUP00000024954	ENSMMUP00000012971	Regulatory factor X1.	Regulatory factor X-associated protein.	0.852
RFX1	SS18L1	ENSMMUP00000024954	ENSMMUP00000050224	Regulatory factor X1.	Uncharacterized protein.	0.573
RFX2	RFXANK	ENSMMUP00000054516	ENSMMUP00000014049	Regulatory factor X2.	Regulatory factor X associated ankyrin containing protein.	0.668
RFX2	RFXAP	ENSMMUP00000054516	ENSMMUP00000012971	Regulatory factor X2.	Regulatory factor X-associated protein.	0.712
RFX2	SS18L1	ENSMMUP00000054516	ENSMMUP00000050224	Regulatory factor X2.	Uncharacterized protein.	0.646
RFX5	CIITA	ENSMMUP00000072291	ENSMMUP00000073242	DNA-binding protein RFX5.	Class II major histocompatibility complex transactivator.	0.993
RFX5	NLRC5	ENSMMUP00000072291	ENSMMUP00000078798	DNA-binding protein RFX5.	NLR family CARD domain containing 5.	0.532
RFX5	RFXANK	ENSMMUP00000072291	ENSMMUP00000014049	DNA-binding protein RFX5.	Regulatory factor X associated ankyrin containing protein.	0.999
RFX5	RFXAP	ENSMMUP00000072291	ENSMMUP00000012971	DNA-binding protein RFX5.	Regulatory factor X-associated protein.	0.998
RFX5	SS18L1	ENSMMUP00000072291	ENSMMUP00000050224	DNA-binding protein RFX5.	Uncharacterized protein.	0.583