STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (468 aa)    
Predicted Functional Partners:
SLURP1
Secreted LY6/PLAUR domain containing 1.
     
 0.918
CHRNA3
Cholinergic receptor nicotinic alpha 3 subunit.
  
0.834
CHRNA1
Cholinergic receptor nicotinic alpha 1 subunit.
  
0.805
CHRNB4
Cholinergic receptor nicotinic beta 4 subunit.
  
0.799
CHRNB2
Neuronal acetylcholine receptor subunit beta-2.
  
0.784
CHRNA7
Neuronal acetylcholine receptor subunit alpha-7; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin (By similarity).
  
0.773
CHRNA2
Cholinergic receptor nicotinic alpha 2 subunit.
  
0.741
CHRNB1
Cholinergic receptor nicotinic beta 1 subunit.
  
0.736
ULK4
Unc-51 like kinase 4.
      
 0.694
CHRND
Cholinergic receptor nicotinic delta subunit.
   
0.664
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.