Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BRWD3Bromodomain and WD repeat domain containing 3. (1792 aa)    
Predicted Functional Partners:
TBC1D7
TBC1 domain family member 7.
      
 0.832
KIF7
Kinesin family member 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.805
RIN2
Ras and Rab interactor 2.
      
 0.798
ACCS
Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.
      
 0.788
SPRED1
Sprouty-related, EVH1 domain-containing protein 1.
      
 0.783
AKT3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 0.770
GPC3
Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
      
 0.769
OFD1
OFD1 centriole and centriolar satellite protein.
    
 
 0.763
EZH2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
    
 0.743
CUL4B
Cullin 4B; Belongs to the cullin family.
   
 
 0.732
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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