TPM3 protein (Macaca mulatta) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

TPM3

Tropomyosin 3; Belongs to the tropomyosin family. (285 aa)

Predicted Functional Partners:

TNNT2

0.984

TPM4

0.963

ACTC1

0.962

TPM2

0.902

TNNC1

0.824

ACTA1

0.800

MYL1

0.789

TNNI2

0.788

CAPZA1

0.741

TNNI3

0.734

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTA1	CAPZA1	ENSMMUP00000029083	ENSMMUP00000052724	Actin alpha 1, skeletal muscle.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.670
ACTA1	MYL1	ENSMMUP00000029083	ENSMMUP00000054851	Actin alpha 1, skeletal muscle.	Myosin light chain 1.	0.718
ACTA1	TNNC1	ENSMMUP00000029083	ENSMMUP00000076075	Actin alpha 1, skeletal muscle.	Troponin C1, slow skeletal and cardiac type.	0.669
ACTA1	TNNI2	ENSMMUP00000029083	ENSMMUP00000006425	Actin alpha 1, skeletal muscle.	Troponin I2, fast skeletal type.	0.446
ACTA1	TNNI3	ENSMMUP00000029083	ENSMMUP00000070180	Actin alpha 1, skeletal muscle.	Troponin T1, slow skeletal type.	0.429
ACTA1	TNNT2	ENSMMUP00000029083	ENSMMUP00000017763	Actin alpha 1, skeletal muscle.	Troponin T2, cardiac type.	0.664
ACTA1	TPM2	ENSMMUP00000029083	ENSMMUP00000021441	Actin alpha 1, skeletal muscle.	Tropomyosin beta chain isoform 2; Belongs to the tropomyosin family.	0.468
ACTA1	TPM3	ENSMMUP00000029083	ENSMMUP00000014158	Actin alpha 1, skeletal muscle.	Tropomyosin 3; Belongs to the tropomyosin family.	0.800
ACTA1	TPM4	ENSMMUP00000029083	ENSMMUP00000076751	Actin alpha 1, skeletal muscle.	Tropomyosin alpha-4 chain isoform 1; Belongs to the tropomyosin family.	0.539
ACTC1	CAPZA1	ENSMMUP00000009222	ENSMMUP00000052724	Actin alpha cardiac muscle 1.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.521
ACTC1	MYL1	ENSMMUP00000009222	ENSMMUP00000054851	Actin alpha cardiac muscle 1.	Myosin light chain 1.	0.596
ACTC1	TNNC1	ENSMMUP00000009222	ENSMMUP00000076075	Actin alpha cardiac muscle 1.	Troponin C1, slow skeletal and cardiac type.	0.480
ACTC1	TNNT2	ENSMMUP00000009222	ENSMMUP00000017763	Actin alpha cardiac muscle 1.	Troponin T2, cardiac type.	0.982
ACTC1	TPM2	ENSMMUP00000009222	ENSMMUP00000021441	Actin alpha cardiac muscle 1.	Tropomyosin beta chain isoform 2; Belongs to the tropomyosin family.	0.943
ACTC1	TPM3	ENSMMUP00000009222	ENSMMUP00000014158	Actin alpha cardiac muscle 1.	Tropomyosin 3; Belongs to the tropomyosin family.	0.962
ACTC1	TPM4	ENSMMUP00000009222	ENSMMUP00000076751	Actin alpha cardiac muscle 1.	Tropomyosin alpha-4 chain isoform 1; Belongs to the tropomyosin family.	0.955
CAPZA1	ACTA1	ENSMMUP00000052724	ENSMMUP00000029083	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Actin alpha 1, skeletal muscle.	0.670
CAPZA1	ACTC1	ENSMMUP00000052724	ENSMMUP00000009222	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Actin alpha cardiac muscle 1.	0.521
CAPZA1	TPM3	ENSMMUP00000052724	ENSMMUP00000014158	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Tropomyosin 3; Belongs to the tropomyosin family.	0.741
MYL1	ACTA1	ENSMMUP00000054851	ENSMMUP00000029083	Myosin light chain 1.	Actin alpha 1, skeletal muscle.	0.718