Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RELREL proto-oncogene, NF-kB subunit. (616 aa)    
Predicted Functional Partners:
NFKB1
Uncharacterized protein.
   
 0.997
NFKBIA
NF-kappa-B inhibitor alpha.
   
 0.987
NFKBIE
NFKB inhibitor epsilon.
   
 0.985
NFKB2
Nuclear factor kappa B subunit 2.
   
 0.981
NFKBIB
NF-kappa-B inhibitor beta isoform a.
   
 0.981
RELA
RELA proto-oncogene, NF-kB subunit.
    
 0.972
RELB
RELB proto-oncogene, NF-kB subunit.
    
 
0.963
TBK1
Serine/threonine-protein kinase TBK1.
   
 0.952
TNIP2
TNFAIP3 interacting protein 2.
   
 0.908
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.905
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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