STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKG1cGMP-dependent protein kinase. (686 aa)    
Predicted Functional Partners:
MRVI1
Murine retrovirus integration site 1 homolog.
   
 0.985
PPP1R12A
Protein phosphatase 1 regulatory subunit.
   
 0.948
KCNMA1
Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...]
   
 
 0.939
KCNU1
Potassium calcium-activated channel subfamily U member 1.
   
 
 0.937
PRKG2
cGMP-dependent protein kinase.
  
  
0.934
GUCY1B1
Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
 0.929
RGS2
Regulator of G-protein signaling 2.
    
 0.925
GUCY1A2
Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
 0.925
GUCY1A1
Guanylate cyclase soluble subunit alpha-3 isoform A; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
 0.925
LIPE
Lipase E, hormone sensitive type.
     
 0.918
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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