Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRRC45Leucine rich repeat containing 45. (670 aa)    
Predicted Functional Partners:
KXD1
KxDL domain-containing protein.
    
  0.754
PAK6
Non-specific serine/threonine protein kinase.
    
   0.692
CEP164
Centrosomal protein 164.
   
 0.689
CNTLN
Centlein.
      
 0.672
TTBK2
Tau-tubulin kinase 2.
   
 
 0.669
CEP89
Centrosomal protein 89.
     
 0.664
CCDC102B
Coiled-coil domain containing 102B.
    
 
 0.663
ANKS3
Ankyrin repeat and sterile alpha motif domain containing 3.
   
  0.620
GIMAP8
GTPase, IMAP family member 8.
   
  0.612
CEP83
Renal carcinoma antigen NY-REN-58.
    
 0.609
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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