STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERC1ELKS/RAB6-interacting/CAST family member 1. (1120 aa)    
Predicted Functional Partners:
RIMS2
Regulating synaptic membrane exocytosis 2.
    
 
 0.851
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.796
PIAS4
Protein inhibitor of activated STAT 4.
      
 0.788
IKBKB
Inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1.
    
 0.786
CSNK1D
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
      
 0.781
CACNA1C
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
    
 
 0.728
PPFIA1
PTPRF interacting protein alpha 1.
    
 
 0.728
FNDC3B
Fibronectin type III domain containing 3B.
      
 0.695
RIMS1
Regulating synaptic membrane exocytosis 1.
    
 
 0.687
PPFIA3
Liprin-alpha-3.
    
 
 0.685
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.