Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EIF4G1Eukaryotic translation initiation factor 4 gamma 1 isoform 6. (1604 aa)    
Predicted Functional Partners:
EIF4E
Uncharacterized protein.
   
 0.995
EIF4G3
Uncharacterized protein.
   
0.993
PABPC1
Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
   
 0.988
EIF4A2
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
 0.985
EIF4G2
Eukaryotic translation initiation factor 4 gamma 2.
   
0.982
EIF4E3
Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.
   
 0.978
EIF3B
Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.
   
 
 0.971
NCBP1
Nuclear cap-binding protein subunit 1.
   
 0.966
ENSMMUP00000077000
RRM domain-containing protein.
   
 0.958
EIF4A1
Eukaryotic initiation factor 4A-I isoform 1; Belongs to the DEAD box helicase family.
   
 0.954
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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