Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF38Rho guanine nucleotide exchange factor 38. (777 aa)    
Predicted Functional Partners:
ARHGEF16
Rho guanine nucleotide exchange factor 16.
     
 0.727
BIN3
Bridging integrator 3.
    
 
 0.707
ARHGEF19
Rho guanine nucleotide exchange factor 19.
     
 0.647
ARHGAP9
Rho GTPase activating protein 9.
    
 
 0.632
NGEF
Neuronal guanine nucleotide exchange factor.
     
 0.610
RHOA
Ras homolog family member A.
    
 0.606
HSPA12B
Heat shock protein family A (Hsp70) member 12B.
   
 
 0.600
HSPA12A
Uncharacterized protein.
   
 
 0.600
ITSN2
Intersectin 2.
   
 0.588
ITSN1
Intersectin 1.
   
 0.588
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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