TNP2 protein (Macaca mulatta) - STRING interaction network

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TNP2

Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. (141 aa)

Predicted Functional Partners:

PRM2

0.944

TNP1

0.944

PINLYP

0.789

MSH4

0.749

OR5AN1

0.746

VWF

0.745

ASF1B

0.685

HMG20B

0.680

PBK

0.675

PLAUR

0.653

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASF1B	HMG20B	ENSMMUP00000018571	ENSMMUP00000064643	Anti-silencing function 1B histone chaperone.	HMG box domain-containing protein.	0.759
ASF1B	PBK	ENSMMUP00000018571	ENSMMUP00000021070	Anti-silencing function 1B histone chaperone.	PDZ binding kinase.	0.865
ASF1B	TNP1	ENSMMUP00000018571	ENSMMUP00000025305	Anti-silencing function 1B histone chaperone.	Transition protein 1.	0.632
ASF1B	TNP2	ENSMMUP00000018571	ENSMMUP00000014367	Anti-silencing function 1B histone chaperone.	Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.	0.685
ASF1B	VWF	ENSMMUP00000018571	ENSMMUP00000053848	Anti-silencing function 1B histone chaperone.	Uncharacterized protein.	0.435
HMG20B	ASF1B	ENSMMUP00000064643	ENSMMUP00000018571	HMG box domain-containing protein.	Anti-silencing function 1B histone chaperone.	0.759
HMG20B	PBK	ENSMMUP00000064643	ENSMMUP00000021070	HMG box domain-containing protein.	PDZ binding kinase.	0.698
HMG20B	TNP1	ENSMMUP00000064643	ENSMMUP00000025305	HMG box domain-containing protein.	Transition protein 1.	0.541
HMG20B	TNP2	ENSMMUP00000064643	ENSMMUP00000014367	HMG box domain-containing protein.	Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.	0.680
MSH4	PRM2	ENSMMUP00000001169	ENSMMUP00000014364	MutS homolog 4.	Protamine-2; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.	0.488
MSH4	TNP1	ENSMMUP00000001169	ENSMMUP00000025305	MutS homolog 4.	Transition protein 1.	0.713
MSH4	TNP2	ENSMMUP00000001169	ENSMMUP00000014367	MutS homolog 4.	Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.	0.749
OR5AN1	PINLYP	ENSMMUP00000018551	ENSMMUP00000068632	Olfactory receptor.	Phospholipase A2 inhibitor and LY6/PLAUR domain containing.	0.855
OR5AN1	PLAUR	ENSMMUP00000018551	ENSMMUP00000006140	Olfactory receptor.	Plasminogen activator, urokinase receptor.	0.741
OR5AN1	TNP2	ENSMMUP00000018551	ENSMMUP00000014367	Olfactory receptor.	Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.	0.746
PBK	ASF1B	ENSMMUP00000021070	ENSMMUP00000018571	PDZ binding kinase.	Anti-silencing function 1B histone chaperone.	0.865
PBK	HMG20B	ENSMMUP00000021070	ENSMMUP00000064643	PDZ binding kinase.	HMG box domain-containing protein.	0.698
PBK	TNP1	ENSMMUP00000021070	ENSMMUP00000025305	PDZ binding kinase.	Transition protein 1.	0.611
PBK	TNP2	ENSMMUP00000021070	ENSMMUP00000014367	PDZ binding kinase.	Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.	0.675
PINLYP	OR5AN1	ENSMMUP00000068632	ENSMMUP00000018551	Phospholipase A2 inhibitor and LY6/PLAUR domain containing.	Olfactory receptor.	0.855

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