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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNP2Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. (141 aa)    
Predicted Functional Partners:
TNP1
Transition protein 1.
   
  
 0.938
PRM2
Protamine-2; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.
   
  
 0.907
PINLYP
Phospholipase A2 inhibitor and LY6/PLAUR domain containing.
   
  
 0.860
MSH4
MutS homolog 4.
      
 0.767
OR5AN1
Olfactory receptor.
      
 0.752
VWF
Uncharacterized protein.
   
 
 0.724
NUPR2
Nuclear protein 2, transcriptional regulator.
      
 0.714
ELOC
Elongin C; Belongs to the SKP1 family.
    
 0.702
SPATA19
Spermatogenesis associated 19.
   
  
 0.676
PLAUR
Plasminogen activator, urokinase receptor.
   
  
 0.676
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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