Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
S100A2Protein S100; Belongs to the S-100 family. (98 aa)    
Predicted Functional Partners:
S100B
Protein S100; Belongs to the S-100 family.
    
 0.820
TCHHL1
Trichohyalin like 1.
    
 
 0.779
S100A3
S100 calcium binding protein A3.
   
 
 0.764
S100A1
S100 calcium binding protein A1; Belongs to the S-100 family.
    
 
 0.754
KPRP
Keratinocyte proline rich protein.
    
 0.629
SORBS3
Sorbin and SH3 domain containing 3.
    
 0.595
KRT5
Keratin 5; Belongs to the intermediate filament family.
   
 0.589
KRT77
Keratin 77; Belongs to the intermediate filament family.
   
 0.525
TRIM10
Tripartite motif-containing 10.
    
 0.459
H1-3
Histone H1.3.
      
 0.456
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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