Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MMP20Uncharacterized protein. (483 aa)    
Predicted Functional Partners:
KLK4
Kallikrein related peptidase 4; Belongs to the peptidase S1 family.
     
 0.947
WDR72
WD repeat domain 72.
      
 0.897
ENAM
RUN and FYVE domain containing 3.
   
  
 0.867
MMP13
Matrix metallopeptidase 13.
   
 0.861
ODAM
Odontogenic ameloblast-associated protein; Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface; Belongs to the ODAM family.
      
 0.818
AMELX
Amelogenin.
      
 0.809
FAM20C
Fam20C domain-containing protein.
     
 0.809
AMBN
Ameloblastin.
   
  
 0.794
FAM83H
Family with sequence similarity 83 member H.
      
 0.767
AMELY
Amelogenin Y-linked.
      
 0.740
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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