Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PANX2Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (676 aa)    
Predicted Functional Partners:
PANX1
Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.
     
0.929
SLC18B1
MFS domain-containing protein.
      
 0.855
ANO8
Anoctamin.
      
 0.721
KCNAB2
Potassium voltage-gated channel subfamily A regulatory beta subunit 2.
      
 0.587
POMGNT2
Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-).
      
 0.580
GRIK5
Glutamate ionotropic receptor kainate type subunit 5.
      
 0.526
KCNK3
Potassium channel subfamily K member.
      
 0.526
KCNG1
Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family.
      
 0.520
CALHM1
Calcium homeostasis modulator 1.
      
 0.520
RIPK4
Receptor interacting serine/threonine kinase 4.
      
 0.485
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.