Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EIF4EUncharacterized protein. (247 aa)    
Predicted Functional Partners:
EIF4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1.
    
 0.999
EIF4G1
Eukaryotic translation initiation factor 4 gamma 1 isoform 6.
   
 0.995
EIF4G3
Uncharacterized protein.
   
 0.991
MKNK1
MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily.
    
 0.983
EIF4EBP2
Eukaryotic translation initiation factor 4E-binding protein 2.
    
 0.980
MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2 isoform 2; Belongs to the protein kinase superfamily.
    
 0.976
EIF4A1
Eukaryotic initiation factor 4A-I isoform 1; Belongs to the DEAD box helicase family.
   
 0.974
EIF4A2
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
 0.972
PAIP1
Polyadenylate-binding protein-interacting protein 1 isoform 1.
   
 0.971
PABPC1
Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
   
 0.965
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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