Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAM21Uncharacterized protein. (722 aa)    
Predicted Functional Partners:
C19orf71
Chromosome 19 open reading frame 71.
   
  
 0.775
KCNC1
BTB domain-containing protein; Belongs to the potassium channel family.
   
  
 0.569
ADAM18
ADAM metallopeptidase domain 18.
   
 0.454
ADAM2
ADAM metallopeptidase domain 2.
   
  0.444
ENSMMUP00000075093
Peptidase M12B domain-containing protein.
   
  0.438
RIMKLA
N-acetylaspartyl-glutamate synthetase A.
      
 0.426
SH3PXD2A
SH3 and PX domains 2A.
    
  0.404
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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