Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KCNH3Potassium voltage-gated channel subfamily H member 3. (1083 aa)    
Predicted Functional Partners:
KCNAB3
Trafficking protein particle complex 1.
    
 0.938
KCNK4
Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
 0.850
OPCML
Opioid binding protein/cell adhesion molecule like.
      
 0.823
CACNB1
Calcium voltage-gated channel auxiliary subunit beta 1.
   
  
 0.811
GABRA5
Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.776
KCNQ3
Potassium voltage-gated channel subfamily KQT member 3 isoform 1; Belongs to the potassium channel family.
   
 
 0.770
SCN1A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
  
 0.731
NTRK2
Tyrosine-protein kinase receptor.
    
 
 0.712
SLC8A2
Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.663
ZNF24
Zinc finger protein 24.
      
 0.660
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.