Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SNX4Sorting nexin 4. (450 aa)    
Predicted Functional Partners:
VAMP1
Vesicle-associated membrane protein 2; Involved in the targeting and/or fusion of transport vesicles to their target membrane. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Belongs to the synaptobrevin family.
    
 0.948
VAMP8
Vesicle-associated membrane protein 8.
   
 0.942
VAMP3
V-SNARE coiled-coil homology domain-containing protein.
    
 0.936
VAMP4
Vesicle-associated membrane protein 4 isoform 1.
    
 0.936
STX7
Syntaxin-7; Belongs to the syntaxin family.
   
 0.936
STX16
Syntaxin-16 isoform a; Belongs to the syntaxin family.
    
 0.932
VAMP7
Vesicle associated membrane protein 7; Belongs to the synaptobrevin family.
     
 0.925
SEC22B
Vesicle-trafficking protein SEC22b; Belongs to the synaptobrevin family.
   
 
 0.918
STX10
Syntaxin 10; Belongs to the syntaxin family.
    
 0.914
STX6
Syntaxin-6; Belongs to the syntaxin family.
    
 0.914
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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