Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MEPEMatrix extracellular phosphoglycoprotein. (555 aa)    
Predicted Functional Partners:
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
     
  0.900
ITGAV
Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.
     
  0.900
PHEX
Phosphate regulating endopeptidase homolog X-linked.
   
 
 0.877
SOST
Sclerostin.
      
 0.853
FGF23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
      
 0.830
DMP1
Dentin matrix acidic phosphoprotein 1.
   
  
 0.828
AMTN
Amelotin.
      
 0.788
PTH
Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.
      
 0.682
IBSP
Integrin binding sialoprotein.
   
  
 0.670
PRKG2
cGMP-dependent protein kinase.
      
 0.633
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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