Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DMP1Dentin matrix acidic phosphoprotein 1. (506 aa)    
Predicted Functional Partners:
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
    
 0.968
ITGAV
Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.
     
 0.939
MEPE
Matrix extracellular phosphoglycoprotein.
   
  
 0.828
IBSP
Integrin binding sialoprotein.
   
  
 0.772
SPP1
Secreted phosphoprotein 1.
  
   
 0.731
FAM20C
Fam20C domain-containing protein.
    
 0.718
PHEX
Phosphate regulating endopeptidase homolog X-linked.
      
 0.711
FGF23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
     
 0.677
ENAM
RUN and FYVE domain containing 3.
  
  
 0.664
ODAM
Odontogenic ameloblast-associated protein; Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface; Belongs to the ODAM family.
      
 0.653
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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