STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1086 aa)    
Predicted Functional Partners:
MEF2B
MADS-box domain-containing protein.
   
 
 0.928
KAT5
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.813
ARID4A
AT-rich interactive domain-containing protein 4A isoform I.
    
 0.795
ARID4B
AT-rich interaction domain 4B.
    
 0.795
NCOR2
Nuclear receptor corepressor 2.
   
 0.770
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
  
 
0.750
NCOR1
Nuclear receptor corepressor 1.
    
 0.739
EP300
Histone acetyltransferase p300.
    
 0.721
MEF2C
Myocyte-specific enhancer factor 2C isoform 1.
   
 
 0.714
MEF2D
Myocyte-specific enhancer factor 2D.
   
 
 0.697
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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