STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SAA1Amyloid protein A; Major acute phase reactant. Apolipoprotein of the HDL complex (122 aa)    
Predicted Functional Partners:
APOA2
Apolipoprotein A-II; Apo A-II makes up about 20% of the protein of the HDL (high density lipoprotein) phospholipid-rich fraction in plasma; Belongs to the apolipoprotein A2 family
   
 
 0.630
APOA1
Uncharacterized protein
   
 0.610
APOE
Apolipoprotein E; Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues; Belongs to the apolipoprotein A1/A4/E family
     
 0.602
SAAL1
Serum amyloid A-like 1
 
    
 0.591
PTX4
Pentraxin 4, long
      
 0.548
PCSK1N
Proprotein convertase subtilisin/kexin type 1 inhibitor
      
 0.456
IL6
Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plas [...]
   
  
 0.451
CRP
Pentaxin
   
  
 0.411
LCN2
Lipocalin 2
   
  
 0.401
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Macaca mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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