FAS protein (Macaca mulatta) - STRING interaction network

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FAS

Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity). (741 aa)

Predicted Functional Partners:

UBB

0.876

FAU

0.868

STAM2

0.849

UBA52

0.848

STAM

0.846

PSMD13

0.799

PSMD6

0.798

PSMD12

0.797

PSMD11

0.783

USP20

0.777

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAS	FAU	ENSMMUP00000061933	ENSMMUP00000024710	Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity).	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.868
FAS	PSMD11	ENSMMUP00000061933	ENSMMUP00000073478	Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity).	Proteasome 26S subunit, non-ATPase 11.	0.783
FAS	PSMD12	ENSMMUP00000061933	ENSMMUP00000002837	Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity).	Proteasome 26S subunit, non-ATPase 12.	0.797
FAS	PSMD13	ENSMMUP00000061933	ENSMMUP00000015107	Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity).	Proteasome 26S subunit, non-ATPase 13.	0.799
FAS	PSMD6	ENSMMUP00000061933	ENSMMUP00000039564	Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity).	Proteasome 26S subunit, non-ATPase 6.	0.798
FAS	STAM	ENSMMUP00000061933	ENSMMUP00000066642	Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity).	Signal transducing adapter molecule 1.	0.846
FAS	STAM2	ENSMMUP00000061933	ENSMMUP00000073889	Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity).	Signal transducing adaptor molecule 2.	0.849
FAS	UBA52	ENSMMUP00000061933	ENSMMUP00000021162	Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity).	Ubiquitin-60S ribosomal protein L40.	0.848
FAS	UBB	ENSMMUP00000061933	ENSMMUP00000050420	Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity).	Uncharacterized protein.	0.876
FAS	USP20	ENSMMUP00000061933	ENSMMUP00000072753	Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity).	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.777
FAU	FAS	ENSMMUP00000024710	ENSMMUP00000061933	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity).	0.868
FAU	PSMD11	ENSMMUP00000024710	ENSMMUP00000073478	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Proteasome 26S subunit, non-ATPase 11.	0.777
FAU	PSMD12	ENSMMUP00000024710	ENSMMUP00000002837	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Proteasome 26S subunit, non-ATPase 12.	0.715
FAU	PSMD13	ENSMMUP00000024710	ENSMMUP00000015107	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Proteasome 26S subunit, non-ATPase 13.	0.761
FAU	PSMD6	ENSMMUP00000024710	ENSMMUP00000039564	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Proteasome 26S subunit, non-ATPase 6.	0.719
FAU	STAM	ENSMMUP00000024710	ENSMMUP00000066642	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Signal transducing adapter molecule 1.	0.581
FAU	STAM2	ENSMMUP00000024710	ENSMMUP00000073889	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Signal transducing adaptor molecule 2.	0.581
FAU	UBA52	ENSMMUP00000024710	ENSMMUP00000021162	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ubiquitin-60S ribosomal protein L40.	0.999
FAU	UBB	ENSMMUP00000024710	ENSMMUP00000050420	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Uncharacterized protein.	0.612
PSMD11	FAS	ENSMMUP00000073478	ENSMMUP00000061933	Proteasome 26S subunit, non-ATPase 11.	Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity).	0.783

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