Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZNF425Zinc finger protein 425. (1096 aa)    
Predicted Functional Partners:
ANTXR1
ANTXR cell adhesion molecule 1.
    
 0.788
TMBIM6
Uncharacterized protein; Belongs to the BI1 family.
      
 0.769
TRIM28
Tripartite motif containing 28.
    
 0.693
PARS2
Prolyl-tRNA synthetase 2, mitochondrial.
    
 
 0.662
NUP85
Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC).
    
   0.610
PCMT1
Protein-L-isoaspartate O-methyltransferase.
      
 0.586
ACOT13
Acyl-CoA thioesterase 13.
      
 0.519
DARS1
Aspartyl-tRNA synthetase, cytoplasmic.
      
 0.504
EMG1
Uncharacterized protein.
      
 0.498
YPEL3
Yippee like 3.
    
 
 0.494
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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