Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDE7APhosphodiesterase. (527 aa)    
Predicted Functional Partners:
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase 3.
    
 0.941
ADK
Adenosine kinase.
     
 0.941
ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase 1.
    
 0.941
ADSL
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.904
AK3
GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
     
 0.904
ENTPD8
Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family.
     
  0.900
ENTPD3
Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.
     
  0.900
NT5E
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
     
 0.835
PDE6C
Phosphodiesterase.
    
0.761
AK8
Adenylate kinase 8; Belongs to the adenylate kinase family.
     
 0.731
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.