Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MKNK2MAP kinase-interacting serine/threonine-protein kinase 2 isoform 2; Belongs to the protein kinase superfamily. (465 aa)    
Predicted Functional Partners:
EIF4E
Uncharacterized protein.
    
 0.976
MAPK1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
0.975
MAPK3
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
0.970
MKNK1
MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily.
  
 
0.944
MAPK14
Mitogen-activated protein kinase.
    
   0.902
ATF4
BZIP domain-containing protein.
     
 0.902
EIF4E2
Eukaryotic translation initiation factor 4E type 2; Belongs to the eukaryotic initiation factor 4E family.
     
  0.900
DGLUCY
D-glutamate cyclase.
      
 0.738
MAPK7
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 
0.552
EIF4G1
Eukaryotic translation initiation factor 4 gamma 1 isoform 6.
   
 
 0.515
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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