Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MBD6Methyl-CpG-binding domain protein 6. (1003 aa)    
Predicted Functional Partners:
MBD5
Uncharacterized protein.
     
0.903
MBD3
Methyl-CpG-binding domain protein 3.
    
 0.738
DENND3
DENN domain containing 3.
   
  
 0.666
MBD4
Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.
    
 0.621
FUT7
Fucosyltransferase 7.
      
 0.601
AMPD3
AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
   
  
 0.571
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.568
MBD2
Methyl-CpG binding domain protein 2.
    
 0.543
SLC16A3
Solute carrier family 16 member 3.
   
 
 0.529
DEFB118
Beta-defensin 118; Has antibacterial activity.
      
 0.486
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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