Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TSPAN16Tetraspanin 16; Belongs to the tetraspanin (TM4SF) family. (224 aa)    
Predicted Functional Partners:
TPM3
Tropomyosin 3; Belongs to the tropomyosin family.
      
 0.593
EIF4E1B
Tetraspanin.
      
 0.588
TSPAN19
Tetraspanin.
      
 0.579
TSPAN31
Tetraspanin-31; Belongs to the tetraspanin (TM4SF) family.
      
 0.578
SEC61A1
Protein transport protein Sec61 subunit alpha isoform 1.
      
 0.523
TSPAN2
Tetraspanin 2; Belongs to the tetraspanin (TM4SF) family.
      
 0.502
TRPC4
ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.486
TRPC5
Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.477
SEC62
SEC62 homolog, preprotein translocation factor.
      
 0.403
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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