SIAH1 protein (Macaca mulatta) - STRING interaction network

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SIAH1

E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)

Predicted Functional Partners:

CACYBP

0.983

CTNNB1

0.981

PINK1

0.942

UBA52

0.941

UBC

0.932

UBB

0.932

RPS27A-2

0.930

MFN2

0.918

MFN1

0.917

FKBP8

0.915

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACYBP	CTNNB1	ENSMMUP00000002100	ENSMMUP00000062910	Calcyclin-binding protein isoform 1.	Catenin beta-1.	0.755
CACYBP	FKBP8	ENSMMUP00000002100	ENSMMUP00000057941	Calcyclin-binding protein isoform 1.	Peptidylprolyl isomerase.	0.528
CACYBP	SIAH1	ENSMMUP00000002100	ENSMMUP00000014922	Calcyclin-binding protein isoform 1.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.983
CTNNB1	CACYBP	ENSMMUP00000062910	ENSMMUP00000002100	Catenin beta-1.	Calcyclin-binding protein isoform 1.	0.755
CTNNB1	RPS27A-2	ENSMMUP00000062910	ENSMMUP00000020417	Catenin beta-1.	Ubiquitin-40S ribosomal protein S27a.	0.510
CTNNB1	SIAH1	ENSMMUP00000062910	ENSMMUP00000014922	Catenin beta-1.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.981
CTNNB1	UBA52	ENSMMUP00000062910	ENSMMUP00000021162	Catenin beta-1.	Ubiquitin-60S ribosomal protein L40.	0.583
CTNNB1	UBB	ENSMMUP00000062910	ENSMMUP00000050420	Catenin beta-1.	Uncharacterized protein.	0.562
CTNNB1	UBC	ENSMMUP00000062910	ENSMMUP00000046819	Catenin beta-1.	Uncharacterized protein.	0.557
FKBP8	CACYBP	ENSMMUP00000057941	ENSMMUP00000002100	Peptidylprolyl isomerase.	Calcyclin-binding protein isoform 1.	0.528
FKBP8	MFN1	ENSMMUP00000057941	ENSMMUP00000005457	Peptidylprolyl isomerase.	Mitofusin-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.920
FKBP8	MFN2	ENSMMUP00000057941	ENSMMUP00000046420	Peptidylprolyl isomerase.	Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.929
FKBP8	PINK1	ENSMMUP00000057941	ENSMMUP00000052968	Peptidylprolyl isomerase.	Serine/threonine-protein kinase PINK1, mitochondrial.	0.552
FKBP8	RPS27A-2	ENSMMUP00000057941	ENSMMUP00000020417	Peptidylprolyl isomerase.	Ubiquitin-40S ribosomal protein S27a.	0.815
FKBP8	SIAH1	ENSMMUP00000057941	ENSMMUP00000014922	Peptidylprolyl isomerase.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.915
FKBP8	UBA52	ENSMMUP00000057941	ENSMMUP00000021162	Peptidylprolyl isomerase.	Ubiquitin-60S ribosomal protein L40.	0.843
FKBP8	UBB	ENSMMUP00000057941	ENSMMUP00000050420	Peptidylprolyl isomerase.	Uncharacterized protein.	0.835
FKBP8	UBC	ENSMMUP00000057941	ENSMMUP00000046819	Peptidylprolyl isomerase.	Uncharacterized protein.	0.816
MFN1	FKBP8	ENSMMUP00000005457	ENSMMUP00000057941	Mitofusin-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Peptidylprolyl isomerase.	0.920
MFN1	MFN2	ENSMMUP00000005457	ENSMMUP00000046420	Mitofusin-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.998

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