MZB1 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

MZB1

DUF3456 domain-containing protein. (188 aa)

Predicted Functional Partners:

TNFRSF17

0.980

JCHAIN

0.952

HSPA5

0.911

POU2AF1

0.911

HYOU1

0.900

MS4A1

0.853

DERL3

0.823

CD79A

0.745

CD3D

0.619

IGHM

0.612

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD3D	CD79A	ENSMMUP00000023161	ENSMMUP00000054745	Ig_4 domain-containing protein.	CD79a molecule.	0.859
CD3D	JCHAIN	ENSMMUP00000023161	ENSMMUP00000064285	Ig_4 domain-containing protein.	Uncharacterized protein.	0.611
CD3D	MS4A1	ENSMMUP00000023161	ENSMMUP00000066984	Ig_4 domain-containing protein.	Membrane spanning 4-domains A1.	0.863
CD3D	MZB1	ENSMMUP00000023161	ENSMMUP00000014926	Ig_4 domain-containing protein.	DUF3456 domain-containing protein.	0.619
CD79A	CD3D	ENSMMUP00000054745	ENSMMUP00000023161	CD79a molecule.	Ig_4 domain-containing protein.	0.859
CD79A	DERL3	ENSMMUP00000054745	ENSMMUP00000011940	CD79a molecule.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.422
CD79A	IGHM	ENSMMUP00000054745	ENSMMUP00000076080	CD79a molecule.	Immunoglobulin heavy constant mu.	0.832
CD79A	JCHAIN	ENSMMUP00000054745	ENSMMUP00000064285	CD79a molecule.	Uncharacterized protein.	0.729
CD79A	MS4A1	ENSMMUP00000054745	ENSMMUP00000066984	CD79a molecule.	Membrane spanning 4-domains A1.	0.976
CD79A	MZB1	ENSMMUP00000054745	ENSMMUP00000014926	CD79a molecule.	DUF3456 domain-containing protein.	0.745
CD79A	POU2AF1	ENSMMUP00000054745	ENSMMUP00000042531	CD79a molecule.	POU class 2 homeobox associating factor 1.	0.763
CD79A	TNFRSF17	ENSMMUP00000054745	ENSMMUP00000028345	CD79a molecule.	TNF receptor superfamily member 17.	0.509
DERL3	CD79A	ENSMMUP00000011940	ENSMMUP00000054745	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	CD79a molecule.	0.422
DERL3	HSPA5	ENSMMUP00000011940	ENSMMUP00000006906	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	78 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family.	0.602
DERL3	HYOU1	ENSMMUP00000011940	ENSMMUP00000036656	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Hypoxia up-regulated 1.	0.549
DERL3	MZB1	ENSMMUP00000011940	ENSMMUP00000014926	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	DUF3456 domain-containing protein.	0.823
DERL3	TNFRSF17	ENSMMUP00000011940	ENSMMUP00000028345	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	TNF receptor superfamily member 17.	0.443
HSPA5	DERL3	ENSMMUP00000006906	ENSMMUP00000011940	78 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.602
HSPA5	HYOU1	ENSMMUP00000006906	ENSMMUP00000036656	78 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family.	Hypoxia up-regulated 1.	0.998
HSPA5	MZB1	ENSMMUP00000006906	ENSMMUP00000014926	78 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family.	DUF3456 domain-containing protein.	0.911