Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NKX2-4NK2 homeobox 4. (356 aa)    
Predicted Functional Partners:
NKX2-1
NK2 homeobox 1.
   
   0.907
SFTPC
Pulmonary surfactant-associated protein C; Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
   
 
 0.650
DCUN1D1
DCN1-like protein.
      
 0.637
FOXA1
Fork-head domain-containing protein.
   
 
 0.609
ZKSCAN3
Zinc finger with KRAB and SCAN domains 3.
    
 
 0.603
ZNF148
Zinc finger protein 148.
    
 
 0.603
ETV3
ETS translocation variant 3 isoform 1.
      
 0.602
ZNF300
Zinc finger protein 300.
    
 
 0.592
PATZ1
POZ/BTB and AT hook containing zinc finger 1.
    
 
 0.585
ZNF219
Zinc finger protein 219.
    
 
 0.571
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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